Intermittent fasting (IF) has gained significant attention in recent years as a dietary pattern with potential health benefits. Beyond its metabolic effects, emerging scientific evidence suggests that intermittent fasting may positively influence skin health. This article reviews the mechanisms by which intermittent fasting affects the skin, including inflammation reduction, cellular regeneration, and hormonal regulation. Introduction The skin is the largest organ of the human body and reflects an individual’s overall health. Skin condition is influenced by several factors, including nutrition, lifestyle, hormonal balance, and oxidative stress. Recently, intermittent fasting has been proposed as a beneficial approach for improving skin health and delaying premature aging. Definition of Intermittent Fasting Intermittent fasting is a dietary regimen that alternates between periods of fasting and eating. Common forms include: The 16:8 method Alternate-day fasting The 5:2 diet This approach focuses primarily on meal timing rather than food type. Mechanisms of Intermittent Fasting on Skin Health 1. Activation of Autophagy Intermittent fasting stimulates autophagy, a cellular process responsible for removing damaged cells and promoting regeneration. This mechanism enhances skin cell renewal and contributes to a healthier and more youthful appearance. 2. Reduction of Inflammation Chronic inflammation plays a key role in skin disorders such as acne, eczema, and psoriasis. Intermittent fasting has been shown to reduce inflammatory markers, thereby improving inflammatory skin conditions. 3. Hormonal Regulation Intermittent fasting helps regulate insulin levels, which may reduce excessive sebum production and prevent clogged pores, ultimately decreasing the incidence of acne. 4. Delay of Skin Aging By reducing oxidative stress and free radical damage, intermittent fasting may slow the appearance of wrinkles, fine lines, and loss of skin elasticity. Positive Effects of Intermittent Fasting on the Skin Improved skin radiance and clarity Reduction in acne and breakouts Enhanced skin cell regeneration More even skin tone Decreased puffiness and fluid retention Potential Negative Effects If not practiced properly, intermittent fasting may lead to: Skin dryness due to inadequate hydration Pale or dull skin caused by nutrient deficiencies Increased hair shedding related to insufficient vitamin and mineral intake Recommendations for Maintaining Skin Health During Intermittent Fasting Maintain adequate hydration throughout the day Consume foods rich in vitamins A, C, and E Include healthy fats such as omega-3 fatty acids Avoid excessive sugar and saturated fat intake Use appropriate skincare products, especially moisturizers Conclusion Intermittent fasting may offer several benefits for skin health when followed in a balanced and well-planned manner. It promotes cellular renewal, reduces inflammation, and may delay signs of aging. However, proper nutritional intake and hydration are essential to avoid potential adverse effects. Al _ Mustaqbal University, the first university in Iraq