Annals of R.S.C.B., ISSN: 1583-6258, Vol. 25, Issue 6, 2021, Pages. 1554-1560<br />Received 25 April 2021; Accepted 08 May 2021.<br />http://annalsofrscb.ro 1554<br />Association of Chronic Helicobacter pylori infection with Iron <br />Deficiency Anemia <br />Qusay Abdulazahraa Yaqoob1<br />, Haider Ali Mahdi2<br />, Hassan Ali Farman3<br />, Mohammed <br />Abdulzahra Sasaa4<br />1University of kufa/Iraq<br />2 Ministry of Health, Al-Sader Medical City, Al-Najaf, Iraq <br />3 Department of Anesthesia and intensive care techniques, college of Health & Medical Techniques, Al-Furat AlAwsat technical university, Iraq.<br />4Al-Mustaqbal University College, Anesthesia techniques department, Hillah, Iraq. <br /> <br />*Corresponding Author’s E-mail: [email protected]<br />Abstract- The study sample consisted of 120 participants divided equally into two groups; 60 <br />patients with H.pylori infectin with iron defeciency anemia and 60 healthy individuals. Their age <br />ranged between 30–70 years, 27 of them were males and 33 were females. H. pylori patients <br />were recruited the Al Sadder Teaching Hospital and the Gastrointestinal Diseases center in AlNajaf AL-Ashraf city, through the duration of December 2019 till February 2020. All patients <br />diagnosed with H.pylori by clinical symptoms and confirmed by H. pylori stool antigen was <br />detected by strips. Verbal consent is taken from each patient before sample. Ten ml of blood are <br />withdrawn by vein puncture from H.pylori patients and healthy control. A tourniquet was applied <br />directly on the skin around the arm, the skin over the vein was sterilized with 70٪ ethyl alcohol, <br />then blood was collected divided into three part; one (2ml) transfer to EDTA tube for estimation <br />of CBC, part two (2ml) was put in ESR tube with anticoagulant and part three (4 ml) put gel tube <br />to be allowed to clot at room temperature for 15-20 minutes, and then it was centrifuged for 5 <br />minutes at 5000xg , to get the serum, the serum was collected for estimation of iron, ferritin, AST <br />and ALT. The result shows that there were statistically significant differences at 0.05 in Hb level <br />between cases (m= 10.91) and controls (m= 14.26), P value 0.000, which means that Hb level <br />was significantly lower among cases compared to controls. In addition, there were statistically <br />non-significant differences at 0.05 in RBC between cases (m= 4.36) and controls (m= 4.55), P <br />value >0.05, which means that RBC were lower among cases compared to controls. In addition, <br />there were statistically significant differences at 0.05 in WBCs between cases (m= 9.76) and <br />controls (m=8.68), P value <0.05, which means that WBCs were significantly higher among <br />cases compared to controls. The results also shows that there were statistically significant <br />differences at 0.05 in PCV level between cases (m= 32.33) and controls (m= 43.01), P value <br />0.000, which means that PCV level was significantly lower among cases compared to controls. <br />Furthermore, there were statistically significant differences at 0.05 in MCV level between cases <br />(m= 63.18) and controls (m=83.56), P value 0.000, which means that MCV level was <br />significantly lower among cases compared to controls. On the other hand, there were statistically <br />insignificant differences between the two groups in levels of MCHC (P=>0.05). In addition, there <br />were statistically significant differences at 0.05 in MCH and PLT between cases and controls P <br />value 0.000. The result also shows that there were statistically significant differences at 0.05 in <br />serum iron, ferritin, AST and ALT level between cases and controls, P value 0.001. In addition, <br />there were statistically significant differences at 0.05 in ESR level between cases and controls P