Fatty liver disease is defined by abnormal accumulation of fat within hepatocytes, usually when fat exceeds 5–10% of liver weight.   Types • Alcoholic fatty liver disease • Non-alcoholic fatty liver disease (NAFLD)   NAFLD may progress to: • Non-alcoholic steatohepatitis (NASH) • Fibrosis • Cirrhosis   Risk Factors • Obesity and central adiposity • Type 2 diabetes mellitus • Insulin resistance • Dyslipidemia • Sedentary lifestyle   Diagnosis • Liver function tests • Ultrasound imaging • FibroScan or liver biopsy in selected cases   Management • Weight reduction • Dietary modification • Regular physical activity • Control of metabolic disorders Roaa Nashat Al-Mustaqbal University The First University in Iraq.