Under the patronage of the Dean of the AL-Mustaqbal College of the University Professor Dr. Hassan Shaker Magdy <br /><br />Thalassemia is a group of genetic disorders caused by an imbalance in the production of one of the four chains of amino acids that make up hemoglobin. It is characterized by a low hemoglobin level and fewer red blood cells than usual. The type of thalassemia depends on the number of genetic mutations and the affected part. The mutation occurs in one or both parts of hemoglobin alpha and beta. Thalassemia occurs due to a genetic mutation in the DNA of hemoglobin-forming cells, and this mutation is transmitted genetically from parents to children. This causes genetic mutations to disrupt the production of normal hemoglobin. Therefore, low hemoglobin levels and a high rate of red blood cell damage (which happens in thalassemia patients) lead to symptoms of anemia. Thalassemia cannot be prevented; Because they are inherited (passed from parents to children through genes). However, tests during pregnancy can detect these blood disorders before birth. Family genetic studies may help to see if people have lost the hemoglobin genes that caused it to change. Thalassemia is a severe type of anemia, and for years people with it were doomed to die at an early age due to the lack of treatment.<br />Still, today, with the tremendous medical development, patients can expect a longer life. Talking with a doctor and a genetic counselor about if there are genetic factors in family history before having children can help determine the risk of passing the disease to children.<br />