Sjögren’s Syndrome and Rheumatoid Arthritis<br />Sjögren’s syndrome (SS) and rheumatoid arthritis (RA) are two distinct yet closely related autoimmune disorders that frequently coexist. Both conditions involve chronic immune-mediated inflammation and share overlapping symptoms, pathophysiological mechanisms, and systemic manifestations. Understanding the relationship between these diseases is critical for accurate diagnosis, effective management, and improving patients' quality of life.<br />Overview of Sjögren’s Syndrome<br />Sjögren’s syndrome is a systemic autoimmune disorder primarily affecting the exocrine glands, resulting in reduced secretion of saliva and tears. It is classified as either primary (occurring alone) or secondary (associated with another autoimmune condition, such as RA). Key symptoms include xerostomia (dry mouth), keratoconjunctivitis sicca (dry eyes), and systemic manifestations like fatigue, joint pain, and organ involvement.<br />