Introduction Diabetes mellitus is a chronic disease that significantly affects the functions of vital organs, especially the kidneys. Kidney failure is a common complication of this disease, which raises the importance of studying the impact of fasting, particularly during the month of Ramadan, on kidney health in diabetic patients. Fasting is associated with physiological changes that may affect the balance of fluids and electrolytes and could potentially pose risks to kidney function. Impact of Fasting on Kidney Functions During fasting periods, individuals abstain from food and drink for extended hours, which may lead to relative dehydration and a reduction in body fluids. This fluid deficit can impact the kidneys, as they heavily rely on fluid balance to perform their critical functions of filtering blood and removing waste products. For diabetic patients, the kidneys are more sensitive to these changes due to damage that may occur to the kidney’s microvasculature as a result of chronic high blood sugar levels. Recommendations for Diabetic Patients During Fasting To ensure the safety of diabetic patients who choose to fast, several important medical precautions must be taken. First, diabetic medications should be adjusted to align with fasting hours to avoid uncontrolled hypoglycemia or hyperglycemia. Second, it is crucial to emphasize proper hydration during the periods of Iftar (breaking the fast) and Suhoor (pre-dawn meal) to maintain kidney function and reduce the risk of dehydration. Third, regular kidney function tests are recommended to monitor any changes that may occur during fasting. Conclusion It can be concluded that fasting during the month of Ramadan can be safe for diabetic patients concerning kidney health if medical guidelines are followed, such as adjusting medications, maintaining hydration, and continuous medical monitoring. Awareness of a healthy diet also plays a key role in reducing risks and promoting kidney safety. Therefore, patients should consult their healthcare providers before fasting and take all necessary precautions to ensure a healthy and safe fasting experience. Al-Mustaqbal University The First University in Iraq