College of Medicine, University of Babylon Discusses a PhD Dissertation

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The College of Medicine at the University of Babylon witnessed the PhD dissertation defense of the student Dunya Mohammed Mubder Al-Birmany, entitled: “Effect of biosynthesized silver nanoparticles from Pseudomonas aeruginosa on carbapenemase and selected virulence genes in Klebsiella pneumoniae.” The defense was attended by Prof. Dr. Mohend Abbass Al-Shalah, Dean of the College of Medicine, Prof. Dr. Lamees Abdulrazzaq Abdul Latif, Head of the Microbiology Department, along with a distinguished group of faculty members and postgraduate students. The Examination Committee • Prof. Dr. Mohammed Abdul-Kadhim Hassan (University of Babylon / College of Medicine) – Chair • Prof. Dr. Jawad Kazim Trad (University of Babylon / College of Medicine) – Member • Prof. Dr. Baydaa Aboud Hassan (University of Kufa / College of Science) – Member • Prof. Dr. Sura Ahsan Abd (University of Babylon / College of Science) – Member • Prof. Dr. Ali Hadi Al-Dhabhawi (University of Babylon / College of Medicine) – Member • Prof. Dr. Bushra Jabbar Hamoud (University of Babylon / College of Medicine) – Member & Supervisor • Asst. Prof. Dr. Rabee’ Mohsen Hassani (University of Babylon / College of Medicine) – Member & Supervisor Study Overview and Key Findings The study introduced an innovative approach by using Pseudomonas aeruginosa to biologically synthesize silver nanoparticles and evaluate their effects on virulence genes and carbapenemase resistance in Klebsiella pneumoniae. The biosynthesized silver nanoparticles demonstrated a strong ability to inhibit the growth of Klebsiella pneumoniae and had a direct impact on both virulence genes and carbapenemase-related resistance. A total of 100 isolates were isolated and confirmed with a 99.7% match using the VITEK-2 system, with absolute resistance (100%) recorded against several conventional antibiotics. The results also showed that combining nanoparticles with antibiotics significantly enhanced the efficacy of beta-lactams and carbapenems. Al-Mustaqbal University is the first university in Iraq Department of Medical Laboratory Techniques – First in the Iraqi National Ranking.