Chronic psychological stress is a persistent condition that negatively affects both physical and mental health. Long-term stress leads to continuous activation of the hypothalamic-pituitary-adrenal axis, resulting in prolonged cortisol secretion. Elevated cortisol levels are associated with weakened immune function, high blood pressure, cardiovascular diseases, and metabolic disorders. Chronic stress also contributes to mental health problems such as anxiety, depression, and sleep disturbances. Studies indicate that stress management strategies, including physical activity, relaxation techniques, and social support, play an important role in reducing stress-related health risks. References: McEwen, B. S. (2007). Cohen, S. et al. (2012). Al-Mustaqbal University the first in Iraq