5
Mar
Adenoid Cystic Carcinoma and HPV Adenoid cystic carcinoma (ACC) is a rare and slow-growing malignant neoplasm that primarily arises in the salivary glands but can also occur in other glandular tissues such as the lacrimal glands, trachea, and breast. It is notable for its unique histological features, including cribriform patterns, perineural invasion, and a propensity for distant metastases rather than lymphatic spread. Human papillomavirus (HPV), a DNA virus associated with a range of cancers, has been implicated in the pathogenesis of various malignancies, particularly those affecting the oropharynx. Recent studies have explored the potential role of HPV in ACC, shedding light on its etiological and prognostic implications.
