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The research described in this paper aimed to identify 222Rn concentrations in the serum of healthy individuals and lung cancer patients. Additionally, CBC parameters such as WBC (White Blood Cell count), RBC (Red Blood Cells), MCH (Mean Corpuscular Hemoglobin), and PLT (Platelets) were measured and their correlation with the corresponding 222Rn concentrations in the serum of the lung cancer patients was investigated. 222Rn concentrations in serum samples were measured using a CR-39 detector. The mean 222Rn concentration in the serum of the patients was 22.62 ± 3.85 Bq/m3, while that in serum of the healthy individuals was 2.72 ± 0.71 Bq/m3. Also, it was found that the mean WBC, RBC, MCH, and PLT levels in the serum of the patients were 7.15 ± 0.58 cells/L, 4.24 ± 0.17 cells/L, 29.23 ± 0.60 pg, and 285.52 ± 21.78 cells/L, respectively. The results revealed statistically significant differences in 222Rn concentrations when comparing the samples of the patients with those of the healthy individuals. In addition, a reasonable correlation was found (p < 0.01) between the 222Rn concentrations and MCH levels in serum of the patients. It is concluded that, given the observed correlations, further studies are necessary to investigate whether there is any causal relationship behind the observed correlations. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.

The presence of heavy elements in the serum of humans may serve as a reliable indicator for establishing the association between it with hyperbilirubinemia. This research aimed to investigate the impact of heavy metals such as chromium (Cr), cadmium (Cd), and lead (Pb) in the serum of Jaundice (hyperbilirubinemia) patients in infant and adult age groups. Sixty serum samples comprised 20 healthy individuals and 40 hyperbilirubinemia patients. The serum concentrations of Cr, Cd, and Pb were measured using atomic absorption spectroscopy (AAS) after sample preparation. The mean concentrations of these elements in the serum of male and female healthy individuals and patients for the two groups were calculated. The results showed a significant increase (p < 0.05) in the Cd element for the infant group of males for patients compared with healthy groups. On the other hand, in adult groups, the results of Pb element for males, Cr, Cd, and Pb for females showed a significant increase (p < 0.05) in patients compared with healthy groups. The results revealed that all heavy metals showed no significant difference (p > 0.05) at different ages (infant and adult) of the patient groups. The results also revealed that heavy metals showed no significant difference (p > 0.05) between males and females in patients, except for Cd in infants and Cr in adult patient groups. The statistical examination using the Statistical Package for the Social Sciences (SPSS) version 23 program disclosed no significant distinctions in the amounts of these substances among the two clusters. However, hyperbilirubinemia patients had higher Cr, Cd, and Pb concentrations than healthy individuals, indicating a possible association, and all values of Cr, Cd, and Pb concentrations in all serum samples were within the threshold limit value according to the American Conference of Governmental Industrial Hygienists (ACGIH). © The Author(s), under exclusive licence to Springer-Verlag London Ltd., part of Springer Nature 2025.