E
ducation
PhD in Pharmaceutics (August 2016 – August 2019) the University of Iowa, Iowa City, IA, USA
advisor: Dr. Maureen d. Donovan
Thesis: Evaluation of Poly D,L Lactic-Co-Glycolic Acid (PLGA) Nanoparticles Uptake Pathways across the
Nasal Mucosa
Graduate Certificate in Biostatistics (August 2016 - December 2017 )
the University of Iowa, Iowa City, IA, USA
Master of Science in pharmaceutics (August 2014 - August 2016) the University of Iowa, Iowa City, IA, USA
Advisor: Dr. Maureen d. Donovan
Thesis: In Vitro Assessment of the Transport of Poly D,L lactic-Co-Glycolic Acid (PLGA) Nanoparticles
Uptake across the Nasal Mucosa
Bachelor of Science in pharmacy (September 2000 - June 2005)
University of Baghdad, Baghdad, Iraq
Skills summary
1- Experimental techniques
• Analytical techniques: HPLC, LC/MS, Fluorescence Spectroscopy, UV/VIS Spectroscopy
• Formulation, product development, drug delivery/ transport studies
• Evaluate the transport of nanoparticulate delivery system and topicals
• Mammalian cell culture, in vitro evaluation of nanoparticle, small molecule transport using the Transwell® inserts and cell-based assays
• Nanoparticles characterization techniques: nanoprecipitation/light scattering techniques, scanning electron microscopy
• Hands-on dissolution, ft-IR, GC, TGA, DSC
2- Computing and software experiences
• Statistical and data analysis software: hands-on SAS, R that applied for preparation/analysis and graphing of data set included in biostatistics classes activity/ final projects
• PK/PD software: hands-on phoenix® WinNonlin for NCA analysis of basic pk parameters required for adv. pharmacokinetics class activities
• Image processing: Image J, hands-on Imaris software
• Other computer software: Excel, PowerPoint, Word, EndNote, Minitab, GraphPad prism
Professional Experience
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Assistant professor of pharmaceutics/ Al Mustaqbal university college/ Babylon/ Iraq (Oct. 2021- present)
Specialist pharmacist / Ad-Diwanyhia health directorate / Iraq (Feb.2006 – Oct. 2021)
Specialist pharmacist at Pharmacy Department/ need estimation section
• Work with health intuitions at Al-Diwanyiah area to plan for their estimated need of medications and medical supplies
• Develop, distribute and monitor MOH policies related to need estimation
Graduate research assistant/College of Pharmacy- the University of Iowa (Aug. 2014 – 2019)
Evaluated the effect of size and surface charge on the endocytic mechanisms of PLGA nanoparticles into the nasal mucosa
• Prepared PLGA nanoparticles within the size range of 50-125 nm and various surface charge
• Conducted nanoparticle uptake studies using excised nasal tissues
• Investigated various endocytic mechanisms involved in nanoparticle uptake across nasal mucosa using pharmacological/chemical inhibitors
Evaluated exocytosis of 60 nm unmodified PLGA nanoparticles from the nasal epithelial cell model
• Developed a confluent epithelial cell layer using RPMI-2650 cells on Transwell® inserts
• Evaluated cell layer integrity through multiple measurements including the expression of the tight junction protein, electrical resistance (TEER), and evaluation of the permeability of transport
markers
• Used cell culture systems to study the extent of nanoparticle exocytosis
Evaluated transdermal permeability of an anti-tick drug (various formulations) across bovine skin (a project in collaboration with Zoetis)
• Developed HPLC and LC/MS methods for quantification
• Evaluated drug permeability across bovine skin using multiple formulations and multiple compositions of receiver side solution using Franz diffusion cells
• Evaluated drug partition coefficient into excised bovine skin
Clinical pharmacist / Ad-Diwanyhia health directorate / Iraq (Feb.2006 – Aug.2013)
Clinical pharmacist / Ad-Diwanyhia teaching hospital (Feb. 2006 – Aug. 2009)
• Participated in the evaluation of patients’ needs through close work with physicians and nurses
• Filled prescriptions and patient education with required dosage and special precautions
• Investigated unusual drug side effects on hospital patients
Clinical pharmacist in the clinical pharmacy section at Ad-Diwanyhia health (Aug. 2009 – 2013) directorate
• Participated in collecting and reporting uncommon side effects that might associate with the use of medications and reported them to the nationally applied pharmacovigilance program
• Aided in the development and spread of the regulations required to ensure that all pharmacists work to meet national medication safety standards
Teaching experience
assistant professor October 2021-present (Al-Mustaqbal University College/ Iraq)
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• Courses: industrial pharmacy II (Fall 2021) for 5th stage students at the department of pharmacy
• Give lectures, lab instruction, managing courses website.
Teaching assistant August 2016-May 2018 including teaching assistant of the year for 2017-2018 school year (University of Iowa)
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• Courses: foundations of pharmaceutical sciences I & II (Fall 2016), foundations of pharmaceutical sciences III (spring 2017), properties of dosage forms I &II (Fall 2017),
the foundation of pharmaceutical sciences I & II (Fall 2017), nutritional supplements in health and disease: mechanisms and actions (Fall 2017), PHAR:4146: drug disposition and pharmacokinetics
(Spring 2018)
• involved in a wide range of classroom instruction, lab preparation and instruction, managing courses website
Guide pharm d students’ research project in Dr. Maureen Donovan s laboratory (the university of Iowa, Apr 2019 – Sep. 2019)
• experiments planning, training students on research techniques and data analysis
• overseeing on students’ laboratory work
• evaluated various slurry formulations of silver sulfadiazine (a project in collaboration with the University of Iowa pharmaceuticals and university of Iowa hospitals and clinics)
• prepared various slurry formulations of silver sulfadiazine
• optimized sample preparation and HPLC analysis method for quantification of silver sulfadiazine
• evaluated physical and chemical stability of the prepared slurry formulations
Publications
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1. Albarki MA, Donovan MD. bigger or smaller? size and loading effects on Nanoparticle Uptake Efficiency in the Nasal Mucosa. AAPS PharmScitech. 2020 21(8):294.
Poster presentations
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2. Albarki M. and Maureen Donovan, In Vitro Assessment of the Transport of Poly D, L Lactic-Co-Glycolic Acid (PLGA) Nanoparticles across the Nasal Mucosa. Health Sciences Research Week 2016 Apr
12-14 university of Iowa, IA
3. Albarki M. and Maureen Donovan, in vitro assessment of the transport of poly d, l lactic-co-glycolic acid (PLGA) nanoparticles across the nasal mucosa. 48th annual PGSRM 2016 Jun 16-18 UMKC
school of pharmacy, MO
4. Albarki M. and Maureen Donovan in vitro assessment of the transport of poly D, L lactic-co-glycolic acid (PLGA) nanoparticles across the nasal mucosa. health sciences research week 2017 Apr
17-21 university of Iowa, IA
5. Albarki M. and Maureen Donovan, mechanisms of poly D, L lactic-Co-glycolic acid (PLGA) nanoparticle uptake across the nasal mucosa. 49th annual PGSRM 2017 Jun 15-17 the university of
Michigan, college of pharmacy, MI
6. Albarki M. and Maureen Donovan, preparation of poly D, L lactic-Co-glycolic acid (PLGA) nanoparticles and evaluation of uptake pathways across the nasal mucosa. 2017 AAPS annual meeting
and exposition 2017 Nov. 12-15, San Diego, CA
7. Albarki M. and Maureen Donovan, evaluation of poly D, L lactic-Co-glycolic acid (PLGA) nanoparticles uptake pathways across the nasal mucosa. 2018 AAPS PharmSci 360 annual
meeting and exposition 2018 Nov. 4-7, Washington DC
Awards and fellowships
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• University of Iowa/graduate college summer fellowships (Summer 2017, 2018)
• University of Iowa/graduate college Ballard and seashore dissertation fellowships (Fall 2018)
• University of Iowa/ College of Pharmacy: pharmaceutics and translational therapeutics teaching
assistant of the year for the 2017-2018 school year
Professional Organizations
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American Association of Pharmaceutical Scientists (AAPS) (Feb.2015 - present)
References (available on request)
Last updated on Nov. 20, 2021