Scopus Research — mohammed faires

OBJECTIVE: Aim: The study aims to detect Association of Program Cell Death Ligand-1(PD-L1) rs4143815 G>C with some Clinical Symptoms and Oral Ulcer Types in Systemic Lupus Erythematosus (SLE). PATIENTS AND METHODS: Materials and Methods: A case control design was suggested in the study enrolled about 60 SLE patients and 20 healthy individuals as a control group, PD-L1 variation implemented using allele specific PCR. RESULTS: Results: The findings showed significant changes in age (<0.011), sex (p<0.000), and non-sig in BMI (p<0.654). in SLE group about 23.3% of patients have a family history, 93.7% suffered from fever, 51.66% have a Butterfly-shaped rash, 73.3% suffered from oral ulcer, single oral ulcer was observed 65.90% and multiple ulcer observed 34.09%. Oral mouth was more frequent (55%) while pharynx ulcer was low frequent (3.3%). The rs4143815 G>C showed three genotypes (GC, CC and GG), Significant association of CC with SLE patients (OR 67.8874, p <0.003), A non-sig association was observed in GG with SLE (OR 5.8571, p <0.395), significant association of C allele with SLE group (OR 1.3529, p< 0.0008). The PD-L1 rs4143815 (G>C) genotyping distribution according to some clinical symptoms showed a non-significant association with all symptoms. The PD-L1 rs4143815 (G>C) genotyping distribution according to oral ulcer sites showed a non-significant association also. CONCLUSION: Conclusions: The present results concluded closed correlation between rs4143815 G>C and SLE patients, but no association was observed with some clinical symptoms and oral ulcer types.

Background: radiotherapy for the treatment of head and neckcancer can produce damage to tissue and specifically salivary glands, causing an alteration in composition of saliva accompanied with oral mucositis. The present study was designed to investigate the changes in saliva components before and after irradiation in comparison to control. Methods: Sixty human male participate in this study. Thirty of them were patients with head and neck cancer prior to and after radiotherapy were evaluated for constituents of saliva and compared with other thirty free of cancer as a control group. Collection of 2ml of stimulated saliva with biochemical analysis of (buffering capacity, salivary amylase and salivary total protein) were done for all subjects. Results: the current findings show an increment in salivary flow rate for irradiate patients compared to control. while reduction in buffer capacity was observed in irradiate patient in comparison to control. Results for both salivary amylase and salivary total protein illustrated a reduction in their concentration before and after irradiation in comparison to control with significant difference value. Conclusion: Radiotherapy affects salivary glands causing alteration in biochemical components of saliva and may cause oral tissue damage. © RJPT. All right reserved.

Objectives: Tooth avulsion is defined as total tooth displacement from the alveolar socket; the best treatment is replantation of the tooth. Human milk influences body health, growth, and development related to the presence of micro and macro nutrient components. This study assessed the effects of human colostrum as a storage medium on the success of tooth replantation. Methods: The upper left incisor of 30 adult male Wistar rats was extracted, and the rats were divided into three groups according to the storage medium of the extracted tooth for replantation: Hank's balanced salt solution (HBSS), tap water, and colostrum groups. The MTT cell viability assay was conducted, and histological evaluation and histomorphometric analyses were performed on postoperative day 45 for identification of pulp necrosis, periodontal hyalinization, percentage of resorbed area, and the periodontal ligament attachment. Results: The colostrum medium showed a higher percentage of cell viability followed by HBSS with statistical significance. Histological findings of the replanted avulsed tooth that soaked in tap water as storage medium showed obvious external and internal root resorption. Pulp necrosis and periodontal ligament hyalinization and with a significant differences values in comparison to HBSS and colostrum groups (p > 0.05), whereas the colostrum group showed new well-reattached periodontal ligament with normal pulp and no evidence of root resorption. Conclusion: Tooth loss is minimized by using human colostrum as storage medium in replantation of an avulsed tooth after a 1 h period compared to HBSS and water. © 2023 Taibah University

Students in colleges of dentistry in Iraq can prescribe some medications during the fourth and fifth year of their undergraduate study of dentistry under the supervision of their seniors in the dental clinics. Numerous researches in many countries all over the world has identified the gaps in pharmacotherapeutic knowledge among dental students, but no such researche was made in Iraq. This study aimed to measure knowledge and awareness of the side effects and drug interactions of the drugs that are mostly prescribed the dental clinics by Iraqi dental students. A cross-sectional study was directed among 890 undergraduate Iraqi dental students using a structured closed-ended online questionnaire regarding their perception, attitude, knowledge, and awareness toward drug prescription. The online survey was done from March to April 2022. The online questionnaires were completed by 890 Iraqi dental students. This study revealed that dental students had made many mistakes during drug prescriptions due to a lack of pharmacological information, especially regarding analgesics and antibiotic prescriptions. Over and irrational prescription of antibiotics was also found. © 2023 by SPC (Sami Publishing Company)

A total of 60 specimens (urine, burn swabs, and wound swabs) from different clinical cases were collected from patients (in different age groups) who admitted to several health centers in Al-Dewaniya General Teaching Hospital, during a period extending from October 2016 to January 2017. Some virulence factors was investigated for 30 isolates only of MRSA using Single and Multiplex PCR For detection virulence factor genes which both coa gene encoding production of coagulase, clfA gene encoding for clumping factor, spa gene encoding for protein A, fnbA gene encoding for fibronectin binding proteins, luks gene encoding production of Panton Valentine Leukocidin (PVL), Results showed that all 30 isolates (100%) were possescoa, clfA, spaand fnbA genes, 13 (43.3%) were possesluks gene. Nanoparticle represented by gold and silver were tested in this study to defect their effect on viability of S.aureus. The results indicated that? Particle were more effective to inhibit the grow that of this bacterium (data are not showing in this paper). © 2009-2018, JGPT. All Rights Reserved.